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Dalfopristin

Dalfopristin Struktur
112362-50-2
CAS-Nr.
112362-50-2
Englisch Name:
Dalfopristin
Synonyma:
RP 54476;Dalfopristin;Dalfopristin Mesylate;Dalfopristin (RP54476);Dalfopristin (as mesylate);Dalfopristin, 10 mM in DMSO;RP-54476,RP 54476,Inhibitor,Dalfopristin,Antibiotic,Bacterial,inhibit;(3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(Diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadi;(3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(DiethylaMino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-diMethyl-3-(1-Methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetr;(3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(Diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
CBNumber:
CB31075198
Summenformel:
C34H50N4O9S
Molgewicht:
690.85
MOL-Datei:
112362-50-2.mol

Dalfopristin Eigenschaften

Schmelzpunkt:
~150°
Siedepunkt:
940.5±65.0 °C(Predicted)
Dichte
1.27±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMSO:113.0(Max Conc. mg/mL);163.57(Max Conc. mM)
Ethanol:100.0(Max Conc. mg/mL);144.75(Max Conc. mM)
Aggregatzustand
Solid
pka
13.18±0.70(Predicted)
Farbe
White to yellow

Sicherheit

Giftige Stoffe Daten 112362-50-2(Hazardous Substances Data)

Dalfopristin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Dalfopristin is a semi-synthetic analogue of ostreogyrcin A (virginiamycin M, pristinamycin IIA, streptogramin A) formed by addition of diethylaminoethylthiol to the 2-pyrroline group of ostreogyrcin, followed by oxidation to the sulphone. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Dalfopristin is used commercially in synergistic combination with quinupristin (70:30). There is little published data on the synthesis, biological or antibiotic activity of dalfopristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains.

Dalfopristin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Dalfopristin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 104)Lieferanten
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Aladdin Scientific
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Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58

112362-50-2()Verwandte Suche:

  • (3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(DiethylaMino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-diMethyl-3-(1-Methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetr
  • Dalfopristin Mesylate
  • RP 54476
  • Dalfopristin
  • (3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(Diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadi
  • 3H-21,18-Nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, 26-[[2-(diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-, (3R,4R,5E,10E,12E,14S,26R,26aS)-
  • (3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(Diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
  • RP-54476,RP 54476,Inhibitor,Dalfopristin,Antibiotic,Bacterial,inhibit
  • Dalfopristin, 10 mM in DMSO
  • Dalfopristin (as mesylate)
  • Dalfopristin (RP54476)
  • 112362-50-2
  • C34H50N4O9S
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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