Dexamethasone 21-phosphate disodium salt
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- CAS-Nr.
- 2392-39-4
- Englisch Name:
- Dexamethasone 21-phosphate disodium salt
- Synonyma:
- decadronphosphate;DEXAMETHASON SODIUM PHOSPHATE;DEXAMETHASONE PHOSPHATE SODIUM;Dexamethasone sodium phosphate for peak identification;1,4-PREGNADIEN-9-ALPHA-FLUORO-16-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 21-PHOSPHATE, DISODIUM SALT;Ak-Dex;Baldex;Decdan;dexagro;Dexagel
- CBNumber:
- CB0153737
- Summenformel:
- C22H28FNa2O8P
- Molgewicht:
- 516.4
- MOL-Datei:
- 2392-39-4.mol
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Dexamethasone 21-phosphate disodium salt Eigenschaften
- Schmelzpunkt:
- 233-235 °C
- alpha
- D +57° (water); D25 +74 ±4° (calcd on water-free and alcohol-free basis, concn of 10 mg/ml): USP XIX, p 124
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: 50 mg/mL, clear, faintly yellow
- Aggregatzustand
- White Powder
- Farbe
- white to off-white
- PH
- pH(10g/l, 25℃) : 7.5～10.5
- Wasserl?slichkeit
- Soluble in water. Slightly soluble in ethanol. Insoluble in dichloromethane.
- Merck
- 13,2960
- BRN
- 6473066
- Stabilit?t:
- Hygroscopic
- InChIKey
- PLCQGRYPOISRTQ-FCJDYXGNSA-L
- SMILES
- [C@@]12([H])C[C@@H](C)[C@](O)(C(=O)COP([O-])([O-])=O)[C@@]1(C)C[C@H](O)[C@]1(F)[C@@]3(C)C=CC(=O)C=C3CC[C@@]21[H].[Na+].[Na+] |&1:0,3,5,15,18,20,22,32,r|
- CAS Datenbank
- 2392-39-4(CAS DataBase Reference)
- EPA chemische Informationen
- Dexamethasone disodium phosphate (2392-39-4)
Dexamethasone 21-phosphate disodium salt Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.
R63:Kann das Kind im Mutterleib m?glicherweise sch?digen.
S-S?tze Betriebsanweisung:
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
White or almost white, very hygroscopic powder.
Verwenden
Dexamethasone 21-phosphate disodium salt acts as an inducer of apoptosis and inhibitor of the sodium phosphate symporter. It is used in the treatment of emetic effects of cancer therapy and epicondylitis. Further, it serves as an activator of food, medicine, glucocorticoid and anti inflammatory.
Definition
ChEBI: An organic sodium salt which is the disodium salt of dexamethasone phosphate.
Sicherheitsprofil
Poison by intravenous
route. Moderately toxic by ingestion and
intraperitoneal routes. Human systemic
effects by intravenous route: peritonitis,
central nervous system, and gastrointestinal
changes. An experimental teratogen. Other
experimental reproductive effects. When
heated to decomposition it emits toxic
fumes of F-, PO,, and Na2O.
Dexamethasone 21-phosphate disodium salt Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Dexamethasone 21-phosphate disodium salt Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 635)Lieferanten
2392-39-4()Verwandte Suche:
- dexadreson
- dexagro
- dexamethasonedisodiumphosphate
- disodiumdexamethasonephosphate
- disodiumsalt,(11beta,16alpha)-y)
- DEXAMETHASONE 21-PHOSPHATE DISODIUM SALT
- DEXAMETHASONE PHOSPHATE DISODIUM SALT
- dexamethasone 21-(disodium phosphate)
- DEXAMETHASONE SODIM PHOSPHATE
- Dexamethasone acetate phosphate
- DEXAMETHASONE 21-PHOSPHATE DISODIUM
- DEXAMETHASONE SODIUM PHOSPHATE BP STANDARD(CRM STANDARD)
- DEXAMETHASONE SODIUM PHOSPHATE BP(CRM STANDARD)
- DEXAMETHASONE SODIUM PHOSPHATE EPD(CRM STANDARD)
- DEXAMETHASONE SODIUM PHOSPHATE MM(CRM STANDARD)
- DEXAMETHASONE SODIUM PHOSPHATE WHO(CRM STANDARD)
- DexamethasoneSodiumPhosphateBp
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11.beta.,16.alpha.)-
- DEXAMETHASONESODIUMPHOSPHATE,POWDER,USP
- Ak-Dex
- Baldex
- Colvasone
- Corson (pharmaceutical)
- Dalalone
- Decdan
- Dexabene
- Dexagel
- Dexamethasone phosphate sodium salt
- Dexamethazone sodium phosphate
- Disodium dexamethasone 21-monophosphate
- Disodium dexamethasone 21-phosphate
- Maxidex Ointment
- Orgadrone
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11β,16α)-
- Dexamethasone 21-Phosphate Disodium Salt Hydrate
- Dexamethasone Sodium Phosphate (350 mg)
- Dexamethasone 21-phosphate disodium salt, >=98%
- 9-FLUORO-11 BETA,17 ALPHA,21-TRIHYDROXY-16 ALPHA-METHYLPREGNA-1,4-DIENE-3,20-DIONE-21-(DIHYDROGENPHOSPHATE)DIS
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-(dihydrogen phosphate) disodium salt
- 21-Phosphate disodium salt
- megacort
- pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonoox
- sodiumdexamethasonephosphate
- soldesam
- solu-decadron
- spersadox
- 9α-Fluoro-16α-methyl-3,20-dioxo-1,4-pregnadiene-11β,17α,21-triol 21-(phosphoric acid disodium) salt
- Phosphoric acid 9α-fluoro-11β,17α-dihydroxy-16α-methyl-3,20-dioxo-1,4-pregnadien-21-yldisodium salt
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-(dihydrogen phosphate) disodium salt (8CI)
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-phosphate disodium salt (6CI)
- Solu-Deca
- 9-Fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione disodium salt
- disodium [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
- disodium [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] phosphate
- disodium [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-3-keto-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] phosphate
- Dexamethasone Sodium Phosphate USP (powder)
- DexaMethasone 21-phosphate disodiu
- DexaMethasone SodiuM Phosphate USP
