779-27-1
中文名稱
7-羥基香豆素-3-羧酸
英文名稱
7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID
CAS
779-27-1
分子式
C10H6O5
分子量
206.15
MOL 文件
779-27-1.mol
更新日期
2025/07/14 17:27:23
779-27-1 結(jié)構(gòu)式
基本信息
中文別名
傘形酮-3-羧酸7-羥基香豆素-3-甲酸
7-羥基香豆素-3-羧酸
7-羥基-3-羧基香豆素
7-羥基-2-氧代-2H-色烯-3-羧酸
7-羥基-2-氧代-2H-苯并吡喃-3-羧酸
7-羥基香豆素-3-羧酸(>98.0%(HPLC))
英文別名
RARECHEM AL BO 2319OTAVA-BB BB7015592710
3-CARBOXY-7-HYDROXYCOUMARIN
UMBELLIFERONE-3-CARBOXYLIC ACID
7-HYDROXYCOUMARIM-3-CARBOXYLIC ACID
7-Hydroxycoumarin-3-carboxylicAcid>
7-Hydroxycoumarin-3-carboxylic acid ,98%
7-hydroxy-2-oxochromene-3-carboxylic acid
7-HYDROXY-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID
7-Hydroxycoumarin-3-carboxylic acid *CAS 779-27-1*
所屬類別
醫(yī)藥中間體：吡喃類化合物物理化學(xué)性質(zhì)
熔點(diǎn)261 °C(lit.)
沸點(diǎn)474.8±45.0 °C(Predicted)
密度1.639±0.06 g/cm3(Predicted)
儲(chǔ)存條件Keep in dark place,Sealed in dry,Store in freezer, under -20°C
溶解度DMF: soluble
酸度系數(shù)(pKa)7.04 ± 0.02, temperature: 23 °C
形態(tài)粉末晶體
顏色Yellow solid;Orange solid;
Off-white powder
最大波長(zhǎng)(λmax)386 nm (Buffer pH 10.0); 339 nm
(Buffer pH 4.0)
BRN384141
生物領(lǐng)域應(yīng)用Chemical dosimeter
for radiation therapy; detecting bacteria;
detecting/sensing hydroxyl radicals; studying
nucleic acids; as a substrate for measuring
carboxylesterases activity, cellulases activity,
β-galactosidases activity, glycosidases activity,
glycosyltransferases activity, hydrolases activity,
4-hydroxycinnamate decarboxylases activity,
β-lactamases activity, phosphatases activity,
sulfatases activity; treating cancer/antitumor
activity
主要應(yīng)用Carbon-dioxide sensor;
chemical sensors based on non-linear optics;
monitoring of cationic photopolymerization processes;
nanomaterials
InChIInChI=1S/C10H6O5/c11-6-2-1-5-3-7(9(12)13)10(14)15-8(5)4-6/h1-4,11H,(H,12,13)
InChIKeyLKLWLDOUZJEHDY-UHFFFAOYSA-N
SMILESC1(=O)OC2=CC(O)=CC=C2C=C1C(O)=O
安全數(shù)據(jù)
警示詞警告
危險(xiǎn)性描述H315-H319-H335
危險(xiǎn)品標(biāo)志Xi
危險(xiǎn)類別碼36/37/38
安全說(shuō)明26-36
WGK Germany3
F8
海關(guān)編碼29329990
制備方法
方法1
6093-71-6
779-27-1
以7-羥基-2-氧代-2H-苯并吡喃-3-羧酸乙酯為原料合成7-羥基-2-氧代-2H-苯并吡喃-3-羧酸的一般步驟：在90℃下，將7-羥基-2-氧代-2H-苯并吡喃-3-羧酸乙酯（2.00g，8.55mmol）溶于水（20ml）中，緩慢加入濃鹽酸（6ml），反應(yīng)混合物回流8小時(shí)。反應(yīng)完成后，將反應(yīng)液冷卻至室溫，過(guò)濾收集沉淀，并用冷水洗滌，得到7-羥基-2-氧代-2H-苯并吡喃-3-羧酸（1.32g，6.41mmol），為淺紅色固體，收率為75%。
參考文獻(xiàn)：
[1] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986, vol. 25, p. 638 - 639
[2] Food Chemistry, 2012, vol. 135, # 4, p. 2872 - 2878
[3] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 5, p. 502 - 506
[4] Chemical Communications, 2017, vol. 53, # 11, p. 1813 - 1816
[5] Patent: CN106279125, 2017, A. Location in patent: Paragraph 0041; 0042
7-羥基香豆素-3-羧酸價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/05/22 | HY-D0114 | 7-羥基香豆素-3-羧酸 3-Carboxy-7-Hydroxycoumarin | 779-27-1 | 100 mg | 708元 |
| 2025/05/22 | HY-D0114 | 7-羥基香豆素-3-羧酸 3-Carboxy-7-Hydroxycoumarin | 779-27-1 | 250 mg | 798元 |
| 2025/05/22 | H1352 | 7-羥基香豆素-3-羧酸 7-Hydroxycoumarin-3-carboxylic Acid | 779-27-1 | 200mg | 260元 |