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76970-77-9

英文名稱 hexahydro-3a,7a-dimethyl-4,7-epoxy-1H-isoindole-1,3(2H)-dione
CAS 76970-77-9
MOL 文件 76970-77-9.mol
76970-77-9 結(jié)構(gòu)式 76970-77-9 結(jié)構(gòu)式

基本信息

英文別名
Cantharidin imide
hexahydro-3a,7a-dimethyl-4,7-epoxy-1H-isoindole-1,3(2H)-dione
4,7-Epoxy-1H-isoindole-1,3(2H)-dione, hexahydro-3A,7A-dimethyl-, (3aalpha,4beta,7beta,7aalpha)-

應(yīng)用領(lǐng)域

用途一
Cantharidin imide is a PP1/2A inhibitor found in Canarthis vesicatoria. It inhibits proliferation of colorectal cancer cells, increases MCP-1, IL-6, and IL-β levels, and inhibits differentiation and resorptive activity of osteoclasts. This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
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