6453-67-4
6453-67-4 結(jié)構(gòu)式
基本信息
焦脫鎂葉綠酸Α甲酯
焦脫鎂葉綠酸A甲酯雜質(zhì)
焦脫鎂葉綠酸-ALPHA 甲酯
PMPCA
INPP5E
KIAA0123
Nsc267052
Chlorophyll Impurity 5
Methyl pyropheophorbide a
Methyl pyrophaeophorbide a
Methyl carbamic pyrophyllate a
PYROPHEOPHORBIDE A METHYL ESTER
物理化學(xué)性質(zhì)
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/05/22 | HY-137473 | 焦脫鎂葉綠酸Α甲酯 Methyl pyropheophorbide-a | 6453-67-4 | 1 mg | 400元 |
| 2025/05/22 | HY-137473 | 焦脫鎂葉綠酸Α甲酯 Methyl pyropheophorbide-a | 6453-67-4 | 5 mg | 900元 |
| 2025/05/22 | HY-137473 | 焦脫鎂葉綠酸Α甲酯 Methyl pyropheophorbide-a | 6453-67-4 | 10 mg | 1500元 |
常見(jiàn)問(wèn)題列表
Pyropheophorbide-a methyl ester (2 μM; 12 h) inhibits the cell cycle progression from the G0/G1-phases and induces apoptosis at the light dosage of 55.6 kJ/m
2
in PC-3M cells.
Pyropheophorbide-a methyl ester (0.2-15 μM; 20 h) has no signi?cant dark cytotoxicity in NCI-h446 cells.
Pyropheophorbide-a methyl ester (0.1-15 μM; 20 h) mediates a dose-dependent photocytotoxicity in the NCI-h446 cells.
Pyropheophorbide-a methyl ester (2-4 μM; 0-24 h) induces apoptosis of NCI-h446 cells in a time-dependent manner.
Pyropheophorbide-a methyl ester (0.5-4 μM; 0-20 h) shows a photocytotoxicity in PC-3M cells.
Apoptosis Analysis
| Cell Line: | PC-3M cells |
| Concentration: | 2 μM |
| Incubation Time: | 12 h |
| Result: | Apoptosis rate was about 0.27%, 6.15%, 20.49%, 50.76%, 65.39%, 64.92%, and 64.37% at 1, 3, 6, 12, 18, and 24 h posttreatment, respectively under the conditions of LC 75 (2 μM+55.6 kJ/m 2 ). |
Pyropheophorbide-a methyl ester (15 mg/kg; tail vein and topical injection) inhibits the growth of PC-3M tumors in mice.
| Animal Model: | Male BALB/c nude mice (6-8 weeks, 16-20 g) bearing PC-3M tumor |
| Dosage: | 15 mg/kg |
| Administration: | Tail vein injection and topical injection |
| Result: | The tumor volume and the weight inhibition rate were 46.78%, 41.84% in tail vein injection group and 78.66%, 72.07% in topical injection group, respectively. |