39718-89-3
39718-89-3 結(jié)構(gòu)式
基本信息
中文別名
胺普芬阿米洛芬
阿明洛芬
2-(4-((2-甲基烯丙基)氨基)苯基)丙酸
英文別名
EB 382Minalfen
Minalfene
alminoprofen
Alminoprofene
Alminoprofeno
rac AlMinoprofen
alminoprofen USP/EP/BP
ALMINOPROFEN(FORR&DONLY)
Alminoprofene [inn-french]
物理化學性質(zhì)
熔點107°
沸點360.1°C (rough estimate)
密度1.0697 (rough estimate)
折射率1.5100 (estimate)
酸度系數(shù)(pKa)4.86±0.50(Predicted)
阿明洛芬價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2025/05/22 | HY-17485 | 阿明洛芬 Alminoprofen | 39718-89-3 | 5 mg | 312元 |
| 2025/05/22 | HY-17485 | 阿明洛芬 Alminoprofen | 39718-89-3 | 10mg | 500元 |
| 2025/05/22 | HY-17485 | 阿明洛芬 Alminoprofen | 39718-89-3 | 10 mM * 1 mLin DMSO | 550元 |
常見問題列表
生物活性
Alminoprofen 是苯丙酸類非甾體抗炎藥 (NSAID)。Alminoprofen 同時具有抑制分泌磷脂酶A2 (sPLA2) 活性和抗環(huán)氧化酶 (COX-2) 的活性。靶點
|
sPLA2
|
COX-2
|
體外研究
Alminoprofen possesses a dual anti-inflammatory action, by inhibiting both sPLA2 but also COX-2. Alminoprofen (from 0 to 50 μM) induces a dose-related inhibitory response on thelevels of PGE2 formed by the CRL-1517 cell line.
體內(nèi)研究
Alminoprofen (100-300 mg/kg; p.o.) exerts an anti-inflammatory activity.
| Animal Model: | Groups of Wistar Rats (Oedema of the paw) |
| Dosage: | 100 mg/kg |
| Administration: | P.o. |
| Result: | Exerted a statistically significant dose-dependent antagonist action lasting throughout the 2-hr observation period. |