21853-11-2
中文名稱
5α-Pregnane-3β,6α-diol-20-one
英文名稱
5α-Pregnane-3β,6α-diol-20-one
CAS
21853-11-2
分子式
C21H34O3
分子量
334.49
MOL 文件
21853-11-2.mol
更新日期
2025/05/04 20:26:35
21853-11-2 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
熔點(diǎn)202-203 °C
沸點(diǎn)469.7±30.0 °C(Predicted)
密度1.117±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)14.72±0.70(Predicted)
形態(tài)Solid
顏色White to off-white
5α-Pregnane-3β,6α-diol-20-one價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/02/08 | HY-109564 | 5α-Pregnane-3β,6α-diol-20-one | 21853-11-2 | 1 mg | 571元 |
| 2025/02/08 | HY-109564 | 5α-Pregnane-3β,6α-diol-20-one 5α-Pregnane-3β,6α-diol-20-one | 21853-11-2 | 10mM * 1mLin DMSO | 883元 |
| 2025/02/08 | HY-109564 | 5α-Pregnane-3β,6α-diol-20-one 5α-Pregnane-3β,6α-diol-20-one | 21853-11-2 | 5mg | 1200元 |
常見問題列表
生物活性
5α-Pregnane-3β,6α-diol-20-one 是一種促進(jìn)有絲分裂的 progesterone 代謝物，可于血清不足時(shí)雄性激素反應(yīng)的前列腺素癌細(xì)胞中產(chǎn)生。體外研究
Progesterone is converted to 5α-pregnane-3β,6α-diol-20-one in human fibroblasts. Pregnenolone and progesterone are avidly metabolized to 5α-pregnan-3β,6α-diol-20-one in the C4.2 cell line, with nearly complete conversions at 24 h and 18 h, respectively. Preferential 5α-pregnan-3β,6α-diol-20-one formation from early steroid precursors is independent of CYP17A1 but rather relies on 3β-HSD activity.