2097784-79-5
中文名稱
BMS-955176(TFA)
英文名稱
BMS-955176(TFA)
CAS
2097784-79-5
分子式
C44H64N2O8S
分子量
781.06
MOL 文件
2097784-79-5.mol

應(yīng)用領(lǐng)域
用途一
GSK3532795, also known as BMS-955176, is a potent, orally active, second-generation HIV-1 maturation inhibitor (MI) that advanced through phase IIb clinical trials. GSK3532795 combines broad coverage of polymorphic viruses (EC50 <15 nM toward a panel of common polymorphisms representative of 96.5% HIV-1 subtype B virus) with a favorable pharmacokinetic profile in preclinical species.