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常見問題列表
生物活性
CX-157 是一個可逆的單胺氧化酶-A (MAO-A) 抑制劑,其 EC50 值為 19.3 ng/mL。靶點
EC50: 19.3 ng/mL (MAO-A)
體內(nèi)研究
CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC 50 of 19.3?ng/mL. CX-157 is an investigational compound currently in development for the treatment of major depressive disorder (MDD). Mechanistic studies in animals have shown that CX-157 acts to inhibit MAO-A activity in a reversible and competitive manner, elevating brain levels of monoamine neurotransmitters.