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1816331-64-2

中文名稱 化合物 T32013
英文名稱 GSK990
CAS 1816331-64-2
分子式 C23H23N7O2
分子量 429.48
MOL 文件 1816331-64-2.mol
1816331-64-2 結(jié)構(gòu)式 1816331-64-2 結(jié)構(gòu)式

基本信息

中文別名
化合物 T32013
英文別名
GSK990

應(yīng)用領(lǐng)域

用途一
GSK990 is a structurally similar compound which is inactive as an IDH1 inhibitor. GSK990 may be used as a native control to GSK864. SK864 has been shown to be selective in vitro for IDH1 over other classes of proteins (7TMs, ion channels, kinases) and chemoproteomic studies with GSK321, an analog of GSK864, confirm selective binding of IDH1 by this chemical series. GSK864 has a pharmacokinetic profile suitable for in vivo studies. (http://www.thesgc.org/chemical-probes/GSK864).
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