160492-56-8
160492-56-8 結構式
基本信息
中文別名
奧沙奈坦 英文別名
SR142801SR-142801
Osanetant
Osanetant >=98% (HPLC)
N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-N-methylacetamide
(R)-N-{{3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl}-4-phenylpiperidin-4-yl}-N-methylacetamine
N-[1-[3-[(3R)-1-Benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-methylacetamide
AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-
Osanetant AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-
物理化學性質
沸點727.9±60.0 °C(Predicted)
密度1.25
儲存條件-20°C
溶解度DMSO：可溶15mg/mL，澄清
酸度系數(pKa)8.33±0.10(Predicted)
形態(tài)粉末
顏色白色至米色
旋光度 (Optical Rotation)[α]/D +18 to +24°, c = 1 in methanol
奧沙奈坦價格(試劑級)
| 報價日期 | 產品編號 | 產品名稱 | CAS號 | 包裝 | 價格 |
| 2025/05/22 | HY-14551 | 奧沙奈坦 Osanetant | 160492-56-8 | 1mg | 2320元 |
| 2025/05/22 | HY-14551 | 奧沙奈坦 Osanetant | 160492-56-8 | 5mg | 5800元 |
| 2025/05/22 | HY-14551 | 奧沙奈坦 Osanetant | 160492-56-8 | 10 mM * 1 mLin DMSO | 7740元 |
常見問題列表
生物活性
Osanetant (SR142801) 是一種選擇性的 NK3 受體拮抗劑。Osanetant 有抗焦慮和抗抑郁的作用，并被研究用于精神分裂癥。靶點
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NK3
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體內研究
Osanetant (SR142801; po; 1-10 mg/kg; 60 min before testing) significantly increases social interaction time.
Osanetant (ip; 5 and 10 mg/kg; 30 min before testing) decreases immobility time.
| Animal Model: | Male Mongolian gerbils of 7 weeks old (50-60 g) |
| Dosage: | 1, 3 and 10 mg/kg |
| Administration: | Po; 60 min before testing |
| Result: | Significantly increased social interaction time. |