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160385-86-4

中文名稱 NORBIOTINAMINE HYDROCHLORIDE
CAS 160385-86-4
分子式 C10H18ClN3O2S
分子量 279.79
MOL 文件 160385-86-4.mol
160385-86-4 結(jié)構(gòu)式 160385-86-4 結(jié)構(gòu)式

基本信息

英文別名
NORBIOTINAMINE HYDROCHLORIDE

物理化學性質(zhì)

儲存條件−20°C
形態(tài)solid

安全數(shù)據(jù)

WGK Germany3

常見問題列表

生物活性
Norbiotinamine hydrochloride 是生物素的一種替代物。Norbiotinamine 可與氨基酸的羧基偶聯(lián)得到具有反向連接的酰胺鍵的反向肽。
體外研究

In order to couple biotin to amino acids, reaction has to be with an amino group. An example is biocytin (biotin lysine). However, Norbiotinamine could be coupled with a carboxylic group of amino acids to give inverse peptides, having the amide linkage oriented in the opposite direction. As an example, Norbiotinamine is coupled with the NHS ester of N-Boc-glutamic acid γ-benzyl ester. The resulting norbiotinylamide of γglutamic acid (VII), obtained after deprotection, is similar to biocytin, but it has a shorter aliphatic chain and an inverted amide bond.

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