144208-62-8
中文名稱
2-(2-(((芐氧基)羰基)氨基)乙氧基)乙基 4-甲基苯磺酸酯
英文名稱
Toluene-4-sulfonic acid 2-(2-benzyloxycarbonylamino-ethoxy)-ethyl ester
CAS
144208-62-8
分子式
C19H23NO6S
分子量
393.45
MOL 文件
144208-62-8.mol
更新日期
2025/03/21 09:55:39
144208-62-8 結(jié)構(gòu)式
基本信息
中文別名
2-(2-(((芐氧基)羰基)氨基)乙氧基)乙基 4-甲基苯磺酸酯 英文別名
2-(2-(((benzyloxy)carbonyl)amino)ethoxy)ethyl 4-methylbenzenesulfonateToluene-4-sulfonic acid 2-(2-benzyloxycarbonylamino-ethoxy)-ethyl ester
物理化學(xué)性質(zhì)
沸點(diǎn)576.3±50.0 °C(Predicted)
密度1.246±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)11.98±0.46(Predicted)
形態(tài)Viscous Liquid
應(yīng)用領(lǐng)域
用途一
2-(2-(((Benzyloxy)carbonyl)amino)ethoxy)ethyl 4-methylbenzenesulfonate is a PEG linker containing a tosyl group and benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.