1227939-82-3
中文名稱
ILORASERTIB
英文名稱
ABT-348
CAS
1227939-82-3
分子式
C25H21FN6O2S
分子量
488.54
MOL 文件
1227939-82-3.mol
更新日期
2025/05/12 15:50:30
1227939-82-3 結(jié)構(gòu)式
基本信息
中文別名
ABT-348 臨床二期化合物ILORASERTIB
英文別名
ABT-348Vilaprisan
A 968660.0
Ilorasertib
Abbott 968660
ILORASERTIB (ABT-348)
N-[4-[4-Amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl]phenyl]-N'-(3-fluorophenyl)urea
Urea, N-[4-[4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl]phenyl]-N'-(3-fluorophenyl)-
anti-tumor,H1299,Platelet-derived growth factor receptor,Inhibitor,ABT 348,antiproliferative activity,AML,VEGFR,Ilorasertib,histone H3 phosphorylation,ABT348,Vascular endothelial growth factor receptor,PDGFR,Aurora Kinase,inhibit,H460 cells,MDS
物理化學(xué)性質(zhì)
沸點(diǎn)675.7±55.0 °C(Predicted)
密度1.47±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度可溶于乙醇
酸度系數(shù)(pKa)13.56±0.70(Predicted)
形態(tài)固體
顏色Off-white to brown