1212257-18-5
1212257-18-5 結(jié)構(gòu)式
基本信息
N-FMOC-S-2-環(huán)丙基甘氨酸
(ALPHAS)-ALPHA-[[芴甲氧羰基]氨基]環(huán)丙烷乙酸
(S)-2-((((9H-芴-9-基)甲氧基)羰基)氨基)-2-環(huán)丙基乙酸
FMOC-L-CYCLOPROPYLGLYCINE/FMOC-L-環(huán)丙基甘氨酸
(S)-Fmoc-cyclopropylglycine
N-Fmoc-S-2-Cyclopropylglycine
Fmoc-(S)-2-cyclopropylglycine
Fmoc-(S)-Amino-cyclopropyl-acetic acid
Fmoc-L-cyclopropylglycine≥ 99% (HPLC, Chiral purity)
N-α-(9-Fluorenylmethoxycarbonyl)-L-α-cyclopropylglycine
(9H-Fluoren-9-yl)MethOxy]Carbonyl Cyclopropylglycine (EE >98%)
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-cyclopropylacetic acid
(2S)-2-cyclopropyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetic acid
物理化學(xué)性質(zhì)
制備方法
28920-43-6
49606-99-7
1212257-18-5
一般步驟：將2.3 g Na2CO3溶于34 mL水中，攪拌下加入氯甲酸-9-芴基甲酯和(S)-2-氨基-2-環(huán)丙基乙酸。反應(yīng)混合物在室溫下攪拌反應(yīng)。反應(yīng)完成后，通過FT-IR和NMR對產(chǎn)物進(jìn)行表征。FT-IR (純): 2669, 2335, 2159, 2106, 1785, 1689, 1550, 1489, 1463, 1433, 1369, 1296, 1253, 1172, 1128, 1001 cm^-1。^1H NMR (CDCl3, 600 MHz): δ = 7.76 (d, 2H, J = 7.2 Hz), 7.60-7.59 (m, 2H), 7.41-7.39 (m, 2H), 7.32-7.30 (m, 2H), 5.36 (d, 1H, J = 6 Hz), 4.45-4.39 (m, 2H), 4.24-4.21 (m, 1H), 3.83-3.81 (m, 1H), 1.14-1.13 (m, 1H), 0.65-0.46 (m, 5H) ppm。^13C NMR (CDCl3, 150 MHz): δ = 176.6, 156.2, 143.9, 143.8, 141.4, 127.9, 127.2, 125.2, 125.1, 120.1, 67.3, 57.4, 47.3, 13.9, 3.4 ppm。HRMS (ESI): m/z [M + Na]^+ 計(jì)算值 C20H19NO4Na 360.1206，實(shí)測值 360.1193。
參考文獻(xiàn)：
[1] Journal of the American Chemical Society, 2016, vol. 138, # 5, p. 1698 - 1708
[2] Patent: WO2016/138288, 2016, A1. Location in patent: Page/Page column 124
| 報(bào)價(jià)日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
| 2025/05/22 | XW02121225718503 | (S)-2-((((9H-芴-9-基)甲氧基)羰基)氨基)-2-環(huán)丙基乙酸 | 1212257-18-5 | 5G | 2126元 |
| 2025/05/22 | XW02121225718502 | (S)-2-((((9H-芴-9-基)甲氧基)羰基)氨基)-2-環(huán)丙基乙酸 | 1212257-18-5 | 1G | 705元 |
| 2025/05/22 | XW02121225718501 | (S)-2-((((9H-芴-9-基)甲氧基)羰基)氨基)-2-環(huán)丙基乙酸 | 1212257-18-5 | 250MG | 197元 |