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ChemicalBook--->CAS DataBase List--->99624-28-9

99624-28-9

99624-28-9 Structure

99624-28-9 Structure
IdentificationBack Directory
[Name]

Kazinol A
[CAS]

99624-28-9
[Synonyms]

Kazinol A
4-[(2S)-7-hydroxy-3,4-dihydro-2H-chromen-2-yl]-3,6-bis(3-methylbut-2-enyl)benzene-1,2-diol
4-[(2S)-7-hydroxy-3,4-dihydro-2H-chromen-2-yl]-3,6-bis(3-methylbut-2-en-1-yl)benzene-1,2-diol
4-[(2S)-3,4-Dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3,6-bis(3-methyl-2-buten-1-yl)-1,2-benzenediol
1,2-Benzenediol, 4-[(2S)-3,4-dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3,6-bis(3-methyl-2-buten-1-yl)-
[Molecular Formula]

C25H30O4
[MDL Number]

MFCD31693119
[MOL File]

99624-28-9.mol
[Molecular Weight]

394.5
Chemical PropertiesBack Directory
[Melting point ]

129-130 °C
[Boiling point ]

583.5±50.0 °C(Predicted)
[density ]

1.166±0.06 g/cm3(Predicted)
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[pka]

9.91±0.40(Predicted)
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Description]

Kazinol A shows strong inhibition of arachidonic acid (AA)-induced platelet aggregation. Kazinol A possesses potent antioxidant activity against 2,2-diphenyl-l-picrylhydrazyl and 2,2′-azino-bis-ethylbenzthiazoline-6-sulfonic acid (ABTS) radicals.
[Uses]

Kazinol A induces cytotoxic effects in human bladder cancer cells, including the cisplatin-resistant T24R2[1].
[Definition]

ChEBI: Kazinol A is a hydroxyflavonoid.
[References]

[1] Park S, et al. Cytotoxic effects of kazinol A derived from Broussonetia papyrifera on human bladder cancer cells, T24 and T24R2.?Phytomedicine. 2016;23(12):1462-1468. DOI:10.1016/j.phymed.2016.08.005
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