| Identification | Back Directory | [Name]
C3D PEPTIDE P16 | [CAS]
99027-06-2 | [Synonyms]
KNRWEDPGKQLYNVEA
C3d Peptide P16 H-Lys-Asn-Arg-Trp-Glu-Asp-Pro-Gly-Lys-Gln-Leu-Tyr-Asn-Val-Glu-Ala-OH
L-Alanine, L-lysyl-L-asparaginyl-L-arginyl-L-tryptophyl-L-α-glutamyl-L-α-aspartyl-L-prolylglycyl-L-lysyl-L-glutaminyl-L-leucyl-L-tyrosyl-L-asparaginyl-L-valyl-L-α-glutamyl- | [Molecular Formula]
C86H131N25O27 | [MDL Number]
MFCD00214596 | [MOL File]
99027-06-2.mol | [Molecular Weight]
1947.11 |
| Hazard Information | Back Directory | [Uses]
C3 Peptide P16, is a 16 amino acid synthetic peptide derived from human C3d, a fragment generated in trypsin-cleaved C3. C3 Peptide P16 enhances in vitro phosphorylation of pp105 and pp100, a cellular component presenting in the human B lymphoma cells[1][2]. | [References]
[1] Sachdeva R, et al. DING proteins from phylogenetically different species share high degrees of sequence and structure homology and block transcription of HIV-1 LTR promoter. PLoS One. 2013 Aug 6;8(8):e69623. DOI:10.1371/journal.pone.0069623
[2] Frade R, et al. A 16 amino acid synthetic peptide derived from human C3d triggers proliferation and specific tyrosine phosphorylation of transformed CR2-positive human lymphocytes and of normal resting B lymphocytes. Biochem Biophys Res Commun. 1992 Oct 30;188(2):833-42. DOI:10.1016/0006-291x(92)91132-a
[3] Lyamani F, et al. A 16 amino-acid synthetic peptide, derived from human C3d, carries regulatory activity on in vitro phosphorylation of a cellular component of the human B lymphoma cells, Raji. Biochem Biophys Res Commun. 1991 Mar 29;175(3):823-30. DOI:10.1016/0006-291x(91)91639-t |
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