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JNJ-40068782 is a new potent, selective, and systemically active positive allosteric modulator of the mGlu2 receptor. | [Uses]
JNJ-40068782 is a potent positive allosteric modulator of the mGlu2 receptor, with the IC50 of 38 nM[1]. | [References]
[1] Hilde Lavreysen, et al. Pharmacological characterization of JNJ-40068782, a new potent, selective, and systemically active positive allosteric modulator of the mGlu2 receptor and its radioligand [3H]JNJ-40068782. J Pharmacol Exp Ther. 2013 Sep;346(3):514-27. DOI:10.1124/jpet.113.204990 |
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