| Identification | Back Directory | [Name]
4-Thiazolidinone, 5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-2-thioxo-, (5Z)- | [CAS]
937012-09-4 | [Synonyms]
DN5355
4-Thiazolidinone, 5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-2-thioxo-, (5Z)- | [Molecular Formula]
C11H7N3OS2 | [MOL File]
937012-09-4.mol | [Molecular Weight]
261.32 |
| Hazard Information | Back Directory | [Uses]
DN5355 is a small molecule compound that targets amyloid β protein (Aβ) and hyperphosphorylated tau protein. DN5355 can inhibit the aggregation of Aβ and tau protein and disaggregate the formed Aβ and tau protein fibers. DN5355 can be used in the study of Alzheimer's disease[1]. | [References]
[1] Sohui Park, et al. Modulation of Amyloid and Tau Aggregation to Alleviate Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease. ACS Pharmacology & Translational Science (2024). DOI:10.3390/ijms24065285 |
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