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ChemicalBook--->CAS DataBase List--->92562-88-4

92562-88-4

92562-88-4 Structure

92562-88-4 Structure
IdentificationBack Directory
[Name]

2',3'-DIDEOXY-3'-FLUORO-GUANOSINE
[CAS]

92562-88-4
[Synonyms]

MIV 210
Lagociclovir
Lagociclovir(MIV-210)
3'-fluoro-2',3'-dideoxyguanosine
2',3'-DIDEOXY-3'-FLUORO-GUANOSINE
Guanosine, 2',3'-dideoxy-3'-fluoro-
[Molecular Formula]

C10H12FN5O3
[MDL Number]

MFCD00882020
[MOL File]

92562-88-4.mol
[Molecular Weight]

269.23
Chemical PropertiesBack Directory
[Melting point ]

253-255 °C (decomp)
[Boiling point ]

633.5±65.0 °C(Predicted)
[density ]

2.01±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

14.44±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Lagociclovir (FLG) is a nucleoside analogue that inhibits wild-type hepatitis B virus (HBV) replication in a human hepatoma cell line permanently expressing HBV[1].
[References]

[1] Jacquard AC, et al. In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2',3'-dideoxy-3'-fluoroguanosine. Antimicrob Agents Chemother. 2006 Mar;50(3):955-61. DOI:10.1128/AAC.50.3.955-961.2006
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