| Identification | Back Directory | [Name]
L-Phenylalanine, 4-[3-(trifluoromethyl)-3H-diazirin-3-yl]- | [CAS]
92367-16-3 | [Synonyms]
L-Phenylalanine, 4-[3-(trifluoromethyl)-3H-diazirin-3-yl]-
(2S)-2-amino-3-[4-[3-(trifluoromethyl)diazirin-3-yl]phenyl]propanoicacid
(S)-2-Amino-3-(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)propanoic acid | [Molecular Formula]
C11H10F3N3O2 | [MOL File]
92367-16-3.mol | [Molecular Weight]
273.211 |
| Hazard Information | Back Directory | [Uses]
H-L-Photo-Phe-OH is a diazirine-containing phenylalanine amino acid and multifunctional
photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (～360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An Fmoc-protected version is also available as 907294. | [reaction suitability]
reaction type: solution phase peptide synthesis |
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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