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ChemicalBook--->CAS DataBase List--->89845-16-9

89845-16-9

89845-16-9 Structure

89845-16-9 Structure
IdentificationBack Directory
[Name]

Gastrofensin AN 5 free base
[CAS]

89845-16-9
[Synonyms]

Gastrofensin AN 5 free base
Carbamic acid, [4-(4-chlorophenyl)-1,2,3,4-tetrahydro-2-methyl-8-isoquinolinyl]-, ethyl ester (9CI)
[Molecular Formula]

C19H21ClN2O2
[MDL Number]

MFCD02183963
[MOL File]

89845-16-9.mol
[Molecular Weight]

344.84
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
Hazard InformationBack Directory
[Uses]

Gastrofensin AN 5, is a 4-phenyl-tetrahydroisoquinoline derivative, that can be used as an antiulcer agent.
[in vivo]

Gastrofensin AN 5 supresses the formation of ulcers in all experimental models. From the broad pharmacological studies of Gastrofensin AN 5 on this model it can be seen that even a dose of 0.100 mg/kg has a high antiulcer activity. The increase of the dose leads to a regular increase of the antiulcer activity, the highest suppression of the ulcer index being reaches at a dose of 1 mg/kg (86.15%). The comparative studies with Ranitidine and Cimetidine on the same experimental models of gastric ulcers show that Gastrofensin AN 5 possesses an antiulcer activity many times higher than that of the above-mentioned drugs[1].

[storage]

Store at -20°C
89845-16-9 suppliers list
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