| Identification | Back Directory | [Name]
AT9283 | [CAS]
896466-76-5 | [Synonyms]
T9283
AT9283
AT9283 USP/EP/BP
AT-9283 L-Lactate
RWYNKTMXFIMBFE-WNQIDUERSA-N
AT 9283, (2S)-2-hydroxy-propanoic acid salt
1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea (S)-2-
(2S)-2-Hydroxypropanoic acid compd. with N-cyclopropyl-N'-[3-[6-(4-morpholinylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]urea | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C22H29N7O5 | [MDL Number]
MFCD12031513 | [MOL File]
896466-76-5.mol | [Molecular Weight]
471.52 |
| Chemical Properties | Back Directory | [Melting point ]
>164°C (dec.) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Off-White |
| Hazard Information | Back Directory | [Uses]
AT-9283 is a potent AuroraA/AuroraB and multi-kinase inhibitor. AT-9283 has shown to inhibit growth and survival of multiple solid tumor cell lines and is efficacious in mouse xenograft models. It is a COVID19-related research product. | [IC 50]
Aurora A: 3 nM (IC50); Aurora B: 3 nM (IC50); JAK3: 1.1 nM (); JAK2: 1.2 nM (); ABL(T315I): 4 nM () |
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| Company Name: |
China Langchem Inc.
|
| Tel: |
0086-21-58956006 |
| Website: |
www.yuhua99.com/ShowSupplierProductsList19141/0_EN.htm |
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
|