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ChemicalBook--->CAS DataBase List--->890091-43-7

890091-43-7

890091-43-7 Structure

890091-43-7 Structure
IdentificationBack Directory
[Name]

O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL
[CAS]

890091-43-7
[Synonyms]

BOC-NH-PEG9-NH2
NHBoc-PEG9-amine
boc-peg-amine (n=9)
Boc-amido-PEG9-amine
BOC-N-AMIDO-PEG9-NH2
Boc-NH-PEG9-CH2CH2NH2
Boc-N-amido-PEG9-Amine
t-Boc-N-amido-PEG9-Amine
t-boc-N-amido-PEG10-amine
O-(2-AMinoethyl )-O`-[2-(Boc-aMino)ethyl ]octaaethylene glycol
tert-Butyl (29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosyl)carbamate
2-Methyl-2-propanyl (29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacos-1-yl)carbamate
O-(2-Aminoethyl)-O'-[2-(Boc-amino)ethyl]octaethylene glycol >=90% (oligomer purity)
31-Amino-5,8,11,14,17,20,23,26,29-nonaoxa-2-azahentriacontanoic acid 1,1-dimethylethyl ester
5,8,11,14,17,20,23,26,29-Nonaoxa-2-azahentriacontanoicacid, 31-amino-, 1,1-dimethylethyl ester
tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
[Molecular Formula]

C25H52N2O11
[MDL Number]

MFCD03453249
[MOL File]

890091-43-7.mol
[Molecular Weight]

556.69
Chemical PropertiesBack Directory
[Boiling point ]

609.8±55.0 °C(Predicted)
[density ]

1.082±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

Soluble in Water, DMSO, DMF, DCM
[form ]

Liquid
[pka]

12.23±0.46(Predicted)
[color ]

Colorless to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
[WGK Germany ]

3
[HS Code ]

2924190090
Hazard InformationBack Directory
[Description]

t-Boc-N-amido-PEG9-amine is a monodisperse PEG reagent containing an amino group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc group can be deprotected under mild acidic conditions to form the free amine.
[Uses]

Boc-amido-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[General Description]

Our highly purified mono-protected homobifunctional polyethylene glycols display oligomer purities of more than 90%. This extremely narrow distribution of oligomers ensures homogeneous products in many applications such as conjugation reactions or introduction of solubilizing units or spacers.
[reaction suitability]

reagent type: cross-linking reagent
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Spectrum DetailBack Directory
[Spectrum Detail]

O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL(890091-43-7)1HNMR
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