| Hazard Information | Back Directory | [Description]
5-(3-Aminoallyl)-2'-deoxyuridine-5'-O-triphosphate (aminoallyl-dUTP) is an amine-modified nucleotide that has been used in the synthesis of fluorescently labeled UTP.1 Incorporation of aminoallyl-dUTP into primers has been used in the generation of fluorescently labeled probes for DNA microarrays and FRET-based assays to measure the activity of reverse transcriptases.2,3 | [Uses]
AA-dUTP tetrasodium is an amine-modified nucleotide that has been used in the synthesis of fluorescently labeled dUTP. | [References]
1. Kuznetsova, V.E., Spitsyn, M.A., Shershov, V.E., et al. Novel fluorescently labeled nucleotides: Synthesis, spectral properties and application in polymerase chain reaction Mendeleev Commun. 26(2),95-98(2016).
2. Xiang, C.C., Kozhich, O.A., Chen, M., et al. Amine-modified random primers to label probes for DNA microarrays Nat. Biotechnol. 20(7),738-742(2002).
3. Krebs, J.F., and Kore, A.R. Novel FRET-based assay to detect reverse transcriptase activity using modified dUTP analogues Bioconjug. Chem. 19(1),185-191(2008). |
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