| Identification | Back Directory | [Name]
Benzenepropanoic acid, 4-chloro-b-[[[[(1S)-2-Methyl-1-(2-Methyl-1-oxopropoxy)propoxy]carbonyl ]aMino]Methyl]-, (bR)- | [CAS]
847353-30-4 | [Synonyms]
XP 19986
arboclofen placabil
Arbaclofen placarbil
Exeporfinium Chloride
Arbaclofen Placarbil 847353-30-4
(3R)-3-(4-chlorophenyl)-4-[[(1S)-2-methyl-1-(2-methylpropanoyloxy)propoxy]carbonylamino]butanoic acid
Benzenepropanoic acid, 4-chloro-b-[[[[(1S)-2-Methyl-1-(2-Methyl-1-oxopropoxy)propoxy]carbonyl ]aMino]Methyl]-, (bR)- | [EINECS(EC#)]
692-848-9 | [Molecular Formula]
C19H26ClNO6 | [MDL Number]
MFCD19443687 | [MOL File]
847353-30-4.mol | [Molecular Weight]
399.866 |
| Hazard Information | Back Directory | [Uses]
Arbaclofen placarbil is a novel transported proagent of the active R-isomer of baclofen. Baclofen is a racemic GABAB receptor agonist | [References]
[1] Lal R, Sukbuntherng J, Tai EH, et al. Arbaclofen placarbil, a novel R-baclofen prodrug: improved absorption, distribution, metabolism, and elimination properties compared with R-baclofen. J Pharmacol Exp Ther. 2009;330(3):911-921. DOI:10.1124/jpet.108.149773 |
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