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Rabdosin B is an ent-kaurene diterpenoid purified from the air-dried aerial parts of Isodon japonica. | [Uses]
Rabdosin B is an ent-kaurene diterpenoid with anticancer effects. Rabdosin B induces DNA damage in cells, and inhibits lettuce root hair development of seedlings[1][2]. | [References]
[1] Lan Ding, et al. Regulation of cell division and growth in roots of Lactuca sativa L. seedlings by the Ent-Kaurene diterpenoid rabdosin B. J Chem Ecol. 2010 May;36(5):553-63. DOI:10.1007/s10886-010-9783-5
[2] Lan Ding, et al. Comparison of cytotoxicity and DNA damage potential induced by ent-kaurene diterpenoids from Isodon plant. Nat Prod Res. 2011 Sep;25(15):1402-11. DOI:10.1080/14786410802267734 |
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