| Identification | Back Directory | [Name]
NZ-419,5-HYDROXY-1-METHYLIMIDAZOLIDINE-2,4-DIONE | [CAS]
84210-26-4 | [Synonyms]
HD003
NZ419
NZ-419
HD 003
HD-003
NZ 419
NZ-419 84210-26-4
5-hydroxy-1-methylhydantoin
1-methyl-5-hydroxy-imidazoline-2,4-dione
5-hydroxy-1-methylimidazolidine-2,4-dione
2,4-Imidazolidinedione, 5-hydroxy-1-methyl-
NZ-419,5-HYDROXY-1-METHYLIMIDAZOLIDINE-2,4-DIONE | [Molecular Formula]
C4H6N2O3 | [MDL Number]
MFCD00899664 | [MOL File]
84210-26-4.mol | [Molecular Weight]
130.1 |
| Hazard Information | Back Directory | [Uses]
NZ 419 (5-Hydroxy-1-methylhydantoin) is a metabolite of creatinine and an antioxidant with oral activity, which has the ability to scavenge hydroxyl radicals (?OH). NZ 419 can inhibit the progression of chronic kidney disease (CKD) in rats[1]. | [References]
[1] Ienaga K, et al. Creatinine and HMH (5-hydroxy-1-methylhydantoin, NZ-419) as intrinsic hydroxyl radical scavengers. Drug Discov Ther. 2011;5(4):162-175. DOI:10.5582/ddt.2011.v5.4.162 |
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