| Identification | Back Directory | [Name]
FACTOR H, HUMAN | [CAS]
80295-65-4 | [Synonyms]
BETA1H GLOBULIN
FACTOR H, HUMAN
COMPLEMENT FACTOR H
Factor H Protein (Rat)
BETA1H GLOBULIN, HUMAN
complement factor H from human plasma | [MDL Number]
MFCD00166551 |
| Hazard Information | Back Directory | [Uses]
Complement factor H (CFH) is a plasma regulator of the complement protein C3b in the alternative pathway of the complement system. Research has shown that binding of CFH is important for pathogenesis of group A streptococcus (GAS), and inhibition of this binding may be an effective management of GAS infections. | [Biochem/physiol Actions]
Complement factor H plays an essential role in the homeostasis of the complement system and in preventing collateral damage to bystander cells and tissues by complement activation. |
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