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ChemicalBook--->CAS DataBase List--->79645-39-9

79645-39-9

79645-39-9 Structure

79645-39-9 Structure
IdentificationBack Directory
[Name]

06:0 DIETHER PC
[CAS]

79645-39-9
[Synonyms]

06:0 DIETHER PC
1,2-DI-O-HEXYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1,2-DI-O-HEXYL-SN-GLYCERO-3-PHOSPHOCHOLINE;06:0 DIETHER PC
(R)-2,3-Bis(hexyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
[Molecular Formula]

C20H44NO6P
[MDL Number]

MFCD02259319
[MOL File]

79645-39-9.mol
[Molecular Weight]

425.55
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

powder
Hazard InformationBack Directory
[Uses]

06:0 Diether PC or 1,2-di-O-hexyl-sn-glycero-3-phosphocholine might be used:
  • in bicelle media to measure the H—C one-bond residual dipolar couplings for trisaccharides, Lewis X (Lex) and Lewis A (Lea) methyl glycosides using nuclear magnetic resonance (NMR) residual dipolar couplings
  • to compose isotropically tumbling small bicelles, to study its size and morphology by 31P NMR and atomic force microscopy (AFM)
  • in bicelle preparation for NMR studies

[Biological Activity]

06:0 Diether PC (phosphocholine) is useful for bicelles preparation. Bicelles can be integrated into standard crystallization protocols and in contrast to micellesbicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. Incorporating 06:0 Diether PC in bicelles results in bicelles similar to conventional phospholipid bicelles but with improved chemical stability.
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