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ChemicalBook--->CAS DataBase List--->77733-28-9

77733-28-9

77733-28-9 Structure

77733-28-9 Structure
IdentificationBack Directory
[Name]

O-(TETRADECYLPHOSPHORYL)CHOLINE 1.5 MM S
[CAS]

77733-28-9
[Synonyms]

MAPCHO-14
Fos-choline-14
n-tetradecylphosphocholine
CHOLINE TETRADECYL PHOSPHATE
n-tetradecylphosphorylcholine
N-TETRADECYLPHOSPHOCHOLINE;MAPCHO-14
n-Tetradecylphosphocholine (unlabelled)
O-(Tetradecylphosphoryl)choline solution
O-(TETRADECYLPHOSPHORYL)CHOLINE 1.5 MM S
O-(Tetradecylphosphoryl)choline 1.5 mM Solution
Tetradecyl (2-(trimethylammonio)ethyl) phosphate
tetradecyl 2-(trimethylazaniumyl)ethyl phosphate
Detergent Screening Solution 39/Fluka kit no 66317
2-[[hydroxy(tetradecyloxy)phosphinyl]oxy]-N,N,N-trimethyl-, inner salt
Ethanaminium,2-[[hydroxy(tetradecyloxy)phosphinyl]oxy]-N,N,N-trimethyl-, inner salt
[EINECS(EC#)]

231-791-2
[Molecular Formula]

C19H42NO4P
[MDL Number]

MFCD00171705
[MOL File]

77733-28-9.mol
[Molecular Weight]

379.52
Chemical PropertiesBack Directory
[Melting point ]

224-226 °C
[storage temp. ]

2-8°C
[solubility ]

DMF: 16 mg/ml; DMSO: 16 mg/ml; Ethanol: 15 mg/ml; PBS (pH 7.2): 25 mg/ml
[form ]

A crystalline solid
[color ]

white to beige
Safety DataBack Directory
[WGK Germany ]

-
Hazard InformationBack Directory
[Uses]

Tetradecyl-phosphocholine is a detergent for membrane protein solubilization.
[Biological Activity]

n-Tetradecylphosphocholine (C14PC)a more stable analog of myristoyl lysophosphatidylcholineis an inhibitor of MARSA virulence. C14PC is a broad-spectrum inhibitor of Panton–Valentine leucocidin (PVL)LukED and α-toxin. C14PC protects primary human immune cells in vitro against cytolysis by PVL and α-toxin. C14PC can be used as a detergent for membrane solubilization.
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