| Identification | Back Directory | [Name]
6-AMINO-7-BROMO-BENZOTHIAZOLE | [CAS]
769-20-0 | [Synonyms]
6-AMINO-7-BROMO-BENZOTHIAZOLE
6-Benzothiazolamine, 7-bromo-
7-BroMobenzo[d]thiazol-6-aMine
7-Bromo-benzothiazol-6-ylamine
Benzothiazole, 6-amino-7-bromo-
7-broMo-1,3-benzothiazol-6-aMine | [Molecular Formula]
C7H5BrN2S | [MDL Number]
MFCD03426350 | [MOL File]
769-20-0.mol | [Molecular Weight]
229.1 |
| Chemical Properties | Back Directory | [Melting point ]
123 °C | [Boiling point ]
359.3±22.0 °C(Predicted) | [density ]
1.836±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [pka]
1.39±0.30(Predicted) | [Appearance]
Light yellow to yellow Solid |
| Hazard Information | Back Directory | [Synthesis]
General procedure: Benzo[d]thiazol-6-amine (100 mg, 0.67 mmol) was dissolved in 6 mL of chloroform, and a chloroform solution (10 mL) of bromine (42 mg, 0.27 mmol) was slowly added dropwise for about 15 minutes. After completion of the reaction, the mixture was concentrated under reduced pressure and the residue was purified by crystallization through a solvent mixture of dichloromethane and methanol (5:1, v/v) to afford 7-bromobenzo[d]thiazol-6-amine (80 mg, 80% yield). | [References]
[1] Patent: WO2010/91310, 2010, A1. Location in patent: Page/Page column 103
[2] Patent: WO2016/161145, 2016, A1. Location in patent: Paragraph 00693
[3] Patent: WO2011/100502, 2011, A1. Location in patent: Page/Page column 55
[4] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 18, p. 5919 - 5923
[5] Journal of the Chemical Society, 1949, p. 355,361 |
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SynAsst Chemical.
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