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ChemicalBook--->CAS DataBase List--->7611-50-9

7611-50-9

7611-50-9 Structure

7611-50-9 Structure
IdentificationBack Directory
[Name]

NITRILOTRIS(METHYLENEPHOSPHONIC ACID), TRISODIUM SALT
[CAS]

7611-50-9
[Synonyms]

NTPO
Nitrilotris(methylphosphpnicacid),trispdium
NITRILOTRIS(METHYLENEPHOSPHONIC ACID), TRISODIUM SALT
trisodium trihydrogen [nitrilotris(methylene)]trisphosphonate
[EINECS(EC#)]

231-520-8
[Molecular Formula]

C3H13NNaO9P3
[MDL Number]

MFCD00211133
[MOL File]

7611-50-9.mol
[Molecular Weight]

323.05
Chemical PropertiesBack Directory
[EPA Substance Registry System]

Phosphonic acid, [nitrilotris(methylene)]tris-, trisodium salt (7611-50-9)
Hazard InformationBack Directory
[Uses]

NTPO trisodium is a DNA damage inducer, causing genomic DNA damage and fragmentation, activating ATR-mediated cell cycle checkpoints. The DNA damaging effects of NTPO trisodium are abrogated by base excision repair (BER) but not nucleotide excision repair (NER)[1].
[References]

[1] Choi JY, et al. Non-thermal plasma-induced apoptosis is modulated by ATR- and PARP1-mediated DNA damage responses and circadian clock. Oncotarget. 2016 May 31;7(22):32980-9. DOI:10.18632/oncotarget.9087
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