| Identification | Back Directory | [Name]
4-Chloropyridine-3-carboxamide | [CAS]
7418-70-4 | [Synonyms]
4-Chloropyridine-3-carboxamide
4-Chloro-3-pyridinecarboxaMide
4-Chloropyridine-3-carboxamide ISO 9001：2015 REACH | [Molecular Formula]
C6H5ClN2O | [MDL Number]
MFCD10574692 | [MOL File]
7418-70-4.mol | [Molecular Weight]
156.57 |
| Chemical Properties | Back Directory | [Boiling point ]
299.5±25.0 °C(Predicted) | [density ]
1.381±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [pka]
14.19±0.50(Predicted) | [Appearance]
Light yellow to yellow Solid |
| Hazard Information | Back Directory | [Synthesis]
Step A: Preparation of 4-chloronicotinamide: 4-chloronicotinic acid (10.00 g, 63.47 mmol) was mixed with SOCl2 (46.30 mL, 634.7 mmol) and heated and refluxed for 4 hours. Upon completion of the reaction, excess SOCl2 was removed by rotary evaporation. toluene (25 mL) was added to the residue and toluene was again removed by rotary evaporation. The resulting oily product was slowly poured into pre-cooled 25 mL of concentrated NH4OH (0 °C). After precipitating the solid, the product was collected by filtration to give 2.7 g of 4-chloronicotinamide in 27.6% yield. | [References]
[1] Patent: US2007/49603, 2007, A1. Location in patent: Page/Page column 47 |
|
| Company Name: |
Synchem OHG
|
| Tel: |
+49 5662 408730 |
| Website: |
www.synchem.de |
|