| Identification | Back Directory | [Name]
DECANOYL M-NITROANILINE | [CAS]
72298-61-4 | [Synonyms]
DEMNA
DECANOYL M-NITROANILINE
N-(3-NITROPHENYL)-DECANAMIDE
Decanoyl m-Nitroaniline Exclusive | [Molecular Formula]
C16H24N2O3 | [MDL Number]
MFCD00416916 | [MOL File]
72298-61-4.mol | [Molecular Weight]
292.37 |
| Chemical Properties | Back Directory | [Melting point ]
72-72.5 °C | [Boiling point ]
456.4±28.0 °C(Predicted) | [density ]
1.097±0.06 g/cm3(Predicted) | [solubility ]
DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.6 mg/ml; Ethanol: 20 mg/ml | [form ]
A crystalline solid | [pka]
14.14±0.70(Predicted) |
| Hazard Information | Back Directory | [Description]
Decanoyl m-Nitroaniline (DemNA) is one of several nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity. FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its endogenous substrate anandamide (arachidonyl ethanolamide; AEA). It also will hydrolyze fatty acid amides with fewer carbons and fewer double bonds than arachidonate. Exposure of DemNA to FAAH activity results in the release of the yellow colorimetric dye m-nitroaniline (ε = 13,500 at 410 nm) This allows the fast and convenient measurement of FAAH activity using a 96 well plate spectrophotometer. | [Uses]
Decanoyl m-Nitroaniline (DemNA) is a nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity (Ab = 410 nm). | [References]
[1] Micha? Biernacki, et al. Redox system and phospholipid metabolism in the kidney of hypertensive rats after FAAH inhibitor URB597 administration. Redox Biol. 2018 May:15:41-50. |
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