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ChemicalBook--->CAS DataBase List--->709026-60-8

709026-60-8

709026-60-8 Structure

709026-60-8 Structure
IdentificationBack Directory
[Name]

IQHNJQKWEMCXAD-YYZTVXDQSA-N
[CAS]

709026-60-8
[Synonyms]

IQHNJQKWEMCXAD-YYZTVXDQSA-N
C16-Sphingosine-1-phosphate
Sphingosine-1-phosphate (d16:1)
[Molecular Formula]

C16H34NO5P
[MOL File]

709026-60-8.mol
[Molecular Weight]

351.42
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

0.3 M NaOH: 4 mg/ml; DMF: <50 μg/ml; DMSO: <50 μg/ml; PBS (pH 7.2): <50 μg/ml
[form ]

A crystalline solid
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
Hazard InformationBack Directory
[Description]

C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate (S1P; ) that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO cells. C16 S1P was increased in postmortem primary open angle glaucoma trabecular meshwork samples.
[Uses]

C16-Sphingosine-1-phosphate is an important regulator of a wide variety of biological processes acting as an endogenous ligand to EDG/S1P receptors.
[Definition]

ChEBI: Hexadecasphing-4-enine-1-phosphate is a sphingoid 1-phosphate that is hexadecasphing-4-enine substituted by a phospho group at position 1. It has a role as a mouse metabolite. It is functionally related to a hexadecasphing-4-enine.
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