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ChemicalBook--->CAS DataBase List--->702668-62-0

702668-62-0

702668-62-0 Structure

702668-62-0 Structure
IdentificationBack Directory
[Name]

Butanamide, 2-[[3-[2-(1-cyclohexen-1-yl)ethyl]-3,4-dihydro-6,7-dimethoxy-4-oxo-2-quinazolinyl]thio]-N-(4-ethylphenyl)-
[CAS]

702668-62-0
[Synonyms]

Butanamide, 2-[[3-[2-(1-cyclohexen-1-yl)ethyl]-3,4-dihydro-6,7-dimethoxy-4-oxo-2-quinazolinyl]thio]-N-(4-ethylphenyl)-
[Molecular Formula]

C30H37N3O4S
[MOL File]

702668-62-0.mol
[Molecular Weight]

535.7
Chemical PropertiesBack Directory
[density ]

1.21±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

13.40±0.70(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

K284-6111 is an orally active inhibitor for protein chitinase 3-like 1 (CHI3L1). K284-6111 reduces the expression of inflammatory proteins such as iNOS, COX-2, GFAP, and Iba-1, inhibits β-secretase and NF-κB, and suppresses Aβ production. K284-6111 ameliorates the Aβ1–42-induced mice memory impairment, and can be used in research about Alzheimer’s Diseases[1].
[References]

[1] Choi JY, et al., K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF-κB-mediated CHI3L1 expression. J Neuroinflammation. 2018 Aug 11;15(1):224. DOI:10.1186/s12974-018-1269-3
702668-62-0 suppliers list
Company Name: Hubei Chuchang Biotech Co., Ltd.
Tel: +undefined15623860702 , +undefined15623860702
Website: www.chuchangbiotech.com/
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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