| Identification | Back Directory | [Name]
2-(Bromomethyl)-6-methylpyridine | [CAS]
68470-59-7 | [Synonyms]
AKOS B016008
ART-CHEM-BB B016008
Bromomethyl)-6-methylpyridine
2-(BROMOMETHYL)-6-METHYLPYRIDINE
6-Methyl-2-(bromomethyl)pyridine
PYRIDINE, 2-(BROMOMETHYL)-6-METHYL-
2-(BroMoMethyl)-6-Methylpyridine 97%
2-(Bromomethyl)-6-methylpyridine ,97%
Pyridine, 2-(bromomethyl)-6-methyl- (6CI, 9CI)
2-(Bromomethyl)-6-methylpyridine ISO 9001：2015 REACH | [Molecular Formula]
C7H8BrN | [MDL Number]
MFCD04967229 | [MOL File]
68470-59-7.mol | [Molecular Weight]
186.05 |
| Chemical Properties | Back Directory | [Melting point ]
38-42 °C | [Boiling point ]
209.9±25.0 °C(Predicted) | [density ]
1.448±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C(protect from light) | [form ]
solid | [pka]
4.16±0.12(Predicted) | [Appearance]
Off-white to pink Solid | [Sensitive ]
Air Sensitive | [InChI]
InChI=1S/C7H8BrN/c1-6-3-2-4-7(5-8)9-6/h2-4H,5H2,1H3 | [InChIKey]
WJFDCFHWFHCLIW-UHFFFAOYSA-N | [SMILES]
C1(CBr)=NC(C)=CC=C1 |
| Hazard Information | Back Directory | [Chemical Properties]
Solid | [Synthesis]
A. Triphenylphosphine (0.4 g × 4, 6.1 mmol) was added to a stirred solution of (6-methylpyridin-2-yl)methanol (640 mg, 5.2 mmol) and carbon tetrabromide (2.77 g, 8.35 mmol) in batch to a solution of dichloromethane (12 mL) at 0 °C, each time at 2 min intervals. The reaction was continued for 30 min. Upon completion of the reaction, the reaction mixture was purified using rapid column chromatography using a hexane solution of 10% ethyl acetate as eluent to afford 2-(bromomethyl)-6-methylpyridine as a crystalline solid (675 mg, 70% yield). | [References]
[1] Journal of the American Chemical Society, 1994, vol. 116, # 18, p. 8410 - 8411
[2] Patent: WO2008/110793, 2008, A1. Location in patent: Page/Page column 112
[3] Patent: WO2008/125839, 2008, A2. Location in patent: Page/Page column 44
[4] Tetrahedron Letters, 2001, vol. 42, # 32, p. 5393 - 5395
[5] Canadian Journal of Chemistry, 2002, vol. 80, # 8, p. 973 - 982 |
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