| Identification | Back Directory | [Name]
Lauryl betaine | [CAS]
683-10-3 | [Synonyms]
ddn
Ammon
c12bet
AM 301
anonbl
bisterml
amipol6s
AMogen S
jbetaine
desimexi
683-10-3
Anon BL-SF
anhitol24b
productddn
swanolam301
amphitol24b
Genagen LAB
MakaM LB 35
culveramcdg
laurylbetain
Lonzaine 12S
anfotericolb
amphitol20bs
ambitericd40
nissananonbl
EMPIGEN BB(R)
EMPIGEN(R) BB
lauryl betaine
Laruyl Betaine
lauryl-n-betaine
n-Dodecyl betaine
LAURYLDIMETHYLBETAIN
Adeka AMphote AB 35L
EMPIGEN BB DETERGENT
Lauryldimethylbetaine
dimethyllaurylbetaine
DiMethyldodecylbetaine
EMPIGEN(R) BB DETERGENT
Lauryl betaine 683-10-3
DODECYL DIMETHYL BETAINE
lauryl-n-methylsarcosine
BS 12 (betaine surfactant)
2-(Dodecyldimethylammonio)
n,n-dimethyldodecylbetaine
Amphiprotic surfactanBS-12
C12H25N(CH3)2CH2CH(OH)CH2SO3
Dodecyldimethylaminioacetate
lauryldimethylammonioacetate
n,n-dimethyl-n-dodecylglycine
N,N-Dimethyl-N-dodecylbetaine
N-DODECYL-N,N-DIMETHYLGLYCINE
BS12 DODECYLE DIMETHYL BETAINE
glycine,dodecyldimethylbetaine
N-Lauryl-N,N-diMethyl-a-betaine
LAURYL DIMETHYLAMINOACETIC ACID
(dodecyldimethylammonio)acetate
Dodecyl Dimethyl Betaine (BS-12)
betainelauryldimethylaminoacetate
2-(DodecyldiMethylaMMonio)acetate
N,N diMethyl-n-laurylbetaine (LNB)
LauryldiMethylaMinoacetate betaine
Lauryl betaine ISO 9001：2015 REACH
3-AZONIA-3,3-DIMETHYLPENTADECANOATE
LAURYLDIMETHYLAMINOACETICACIDBETAINE
2-[dodecyl(dimethyl)azaniumyl]acetate
N,N-DIMETHYL-N-DODECYLGLYCINE BETAINE
Laury dimethylaminoacetic acid betaine
N,N-DiMethyl-N-laurylglycine Inner Salt
Dimethyllauryl(carboxylatomethyl)aminium
(carboxylatomethyl)dodecyldimethylammonium
35% Lauryl Dimethylaminoacetic Acid Solution
N-(ALKYL C10-C16)-N,N-DIMETHYLGLYCINE BETAINE
carboxymethyl-dodecyl-dimethyl-ammonium betaine
N,N-Dimethyl-N-(carboxylatomethyl)laurylaminium
N,N-Dimethyl-N-(carboxylatomethyl)dodecylaminium
sodium 2-[lauryl(dimethyl)ammonio]acetate chloride
N,N-Dimethyl-N-(carboxylatomethyl)-1-dodecanaminium
2-(Dodecyldimethylammonio)acetate, 30% aqueous (w/w)
sodium 2-[dodecyl(dimethyl)azaniumyl]acetate chloride
Carboxy betaine 683-10-3 N-Dodecyl-N,N-Dimethylglycine
sodium 2-[dodecyl(dimethyl)azaniumyl]ethanoate chloride
1-Dodecanaminium,N-(carboxymethyl)-N,N-dimethyl-,innersalt
N-(Carboxymethyl)-N,N-dimethyl-1-dodecanaminium, inner salt
ammonium,(carboxymethyl)dodecyldimethyl-,hydroxide,innersalt
N-(CarboxyMethyl)-N-lauryldiMethylaMMoniuM Hydroxide Inner Salt
1-dodecanaminium,n-(carboxymethyl)-n,n-dimethyl-,hyroxide,innersalt
1-dodecanaminium,n-(carboxymethyl)-n,n-dimethyl-,hydroxide,innersalt | [EINECS(EC#)]
266-368-1 | [Molecular Formula]
C16H33NO2 | [MDL Number]
MFCD00084742 | [MOL File]
683-10-3.mol | [Molecular Weight]
271.44 |
| Chemical Properties | Back Directory | [Boiling point ]
414.52°C (rough estimate) | [density ]
1.04 g/mL at 20 °C
| [vapor pressure ]
16.796hPa at 21.1℃ | [refractive index ]
1.4545 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Specific Gravity]
1.03 | [Water Solubility ]
464g/L at 25℃ | [λmax]
λ: 260 nm Amax: ≤0.20
λ: 280 nm Amax: ≤0.15 | [BRN ]
3670807 | [Stability:]
Hygroscopic | [LogP]
0.07 at 25℃ | [Uses]
lauryl betaine is a skin-conditioning agent. In hair care, it is used as an anti-static conditioning agent and a foam booster. | [EPA Substance Registry System]
1-Dodecanaminium, N-(carboxymethyl)-N,N-dimethyl-, inner salt(683-10-3) |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of lauryl betaine from dodecanol and methyl 2-(dimethylamino)acetate:
1. Preparation of lauryl N,N-dimethylglycinate: in a 1 L three-necked flask fitted with a Dean-Stark separator, methyl 2-dimethylaminoacetate (189 g; 1.61 mol; 1.5 eq.), lauryl alcohol (200 g; 1.07 mol) and Novozym 435 (20 g) were added. Subsequently 80 ml of heptane was added as solvent. The reaction mixture was heated in an oil bath at 65 °C and the system pressure was adjusted to about 110 mm Hg to promote efficient separation of the heptane/methanol azeotrope. After 5 hours of reaction, 99.1% conversion of the product was confirmed by NMR analysis. Upon completion of the reaction, the reaction mixture was filtered to remove the enzyme catalyst, the enzyme catalyst was washed with heptane, and the filtrates were combined and concentrated to afford 289 g of lauryl N,N-dimethylamino glycinate in 99% yield.
Product Characterization:
1H NMR (500MHz, CDCl3) δ 4.13 (t, 2H); 3.16 (s, 2H); 2.35 (s, 6H); 1.64 (m, 2H); 1.26 (s, 18H); 0.88 (t, 3H).
HPLC analytical conditions: 150 × 4.6 mm Zorbax SB-C8 column, mobile phase initially 75:25 (v:v) methanol:water (containing 0.1% trifluoroacetic acid), gradient to 100% methanol in 1 min, hold for 9 min, ELSD detector, retention time (tR) of 5.2 min. | [References]
[1] Patent: WO2017/48528, 2017, A1. Location in patent: Paragraph 0170-0173 |
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