| Identification | Back Directory | [Name]
THP-PEG10 | [CAS]
658858-65-2 | [Synonyms]
THP-PEG9
THP-PEG10
OH-PEG8-THP
THP-PEG8-OH
3,6,9,12,15,18,21-Heptaoxatricosan-1-ol, 23-[(tetrahydro-2H-pyran-2-yl)oxy]- | [Molecular Formula]
C21H42O10 | [MDL Number]
MFCD29764333 | [MOL File]
658858-65-2.mol | [Molecular Weight]
454.55 |
| Hazard Information | Back Directory | [Description]
THP-PEG8 is a PEG linker with a THP protecting group. The THP is an alcohol protecting group that can be removed under acidic conditions. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. | [Uses]
THP-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
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