| Identification | Back Directory | [Name]
4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic acid dipotassium salt | [CAS]
65664-81-5 | [Synonyms]
BIS-ANS
Bis-ANS dipotassium
BIS-ANS DIPOTASSIUM SALT
bis-ANS (potassium salt)
4,4'-DIANILINO-1,1'-BINAPHTHYL-5,5'-
8-Anilino-1-naphthalenesulfonic Acid Di
4,4'-dianilino-1,1'-binaphthyl-5,5'-di-sulfonic A
4,4'-DIANILINO-1,1'-BINAPHTHYL-5,5'-DISU LFONIC ACI
4,4'-dianilino-1,1'-binaphthyl-5,5'-disulfonic acid, dipot
4,4'-DIANILINO-1,1'-BINAPHTHALENE-5,5'- DISULF.AC. DIPO-SLT*
4,4'-Bis(1-anilinonaphthalene-8-sulfonic Acid) DipotassiuM Salt
BIS-(5,5')-8-ANILINO-1-NAPHTHALENE SULFONIC ACID DIPOTASSIUM SALT
4,4'-DIANILINO-1,1'-BINAPHTHYL-5,5'-DISULFONIC ACID, POTASSIUM SALT
4,4'-DIANILINO-1,1'-BINAPHTHYL-5,5'-DISULFONIC ACID DIPOTASSIUM SALT
4,4''-Dianilino-1,1''-binaphthyl-5,5''-disulfonic acid
dipotassium salt
Bis-ANS [4,4'-Dianilino-1,1'-biphthyl-5,5'-disulfonic acid, dipotassium salt]
4,4'-Bis(phenylaMino)-[1,1'-binaphthalene]-5,5'-disulfonic Acid PotassiuM Salt | [Molecular Formula]
C32H22K2N2O6S2 | [MDL Number]
MFCD00011592 | [MOL File]
65664-81-5.mol | [Molecular Weight]
672.85 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C, protect from light | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: slightly soluble; PBS (pH 7.2): 5 mg/ml | [form ]
A crystalline solid | [color ]
light yellow
| [Appearance]
light yellow-green crystals | [BRN ]
5714637 |
| Hazard Information | Back Directory | [Description]
Bis-ANS is a high-affinity fluorescent probe for nonpolar cavities in proteins. Its hydrophobic phenyl and naphthyl rings interact noncovalently with proteins and protein degradation products.
As with other anilinonaphthalene sulfonates (ANS), bis-ANS is essentially nonfluorescent in water but becomes noticeably fluorescent in a nonpolar environment. When free, bis-ANS has an excitation maximum at 390 nm and an emission maximum at 523 nm but undergoes a blue shift with an increase in fluorescence intensity when bound to protein.
Bis-ANS is frequently used to monitor the formation of protein aggregates and indicate protein folding and conformational changes. The dye is also used to detect Aβ fibers. | [Uses]
4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic Acid is a bifunctional fluorescent probe for proteins. | [storage]
Store at -20°C, protect from light | [Abs/Em Maxima]
396 (free), 401 (complex)/508 (free), 488 (complex) nm | [Excitation / Emission Maximum]
390 nm (free), 484 nm (bound)/523 nm (free), 496 nm (bound) |
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Sigma-Aldrich
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