| Identification | Back Directory | [Name]
19(R)-HYDROXY PROSTAGLANDIN E1 | [CAS]
64625-55-4 | [Synonyms]
19(R)-hydroxy PGE1
QVVXWHIDRKRPMO-VOSXNNSYSA-N
19(R)-HYDROXY PROSTAGLANDIN E1
19(R)-hydroxy Prostaglandin E1
9-oxo-11α,15S,19R-trihydroxy-prost-13E-en-1-oic acid
9-OXO-11ALPHA,15S,19R-TRIHYDROXY-PROST-13E-EN-1-OIC ACID
Prost-13-en-1-oic acid, 11,15,19-trihydroxy-9-oxo-, (11α,13E,15S,19R)- | [Molecular Formula]
C20H34O6 | [MDL Number]
MFCD00135212 | [MOL File]
64625-55-4.mol | [Molecular Weight]
370.48 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1) |
| Hazard Information | Back Directory | [Description]
19(R)-hydroxy PGE1 is the major prostaglandin found in the semen of primates, including man. It is an agonist for the EP1 and EP3 receptor subtypes, and exhibits contractile activity on smooth muscle preparations. It has an EC50 of 320 nM for contracting guinea pig ileum, which express EP1 receptors, and an EC50 of 80 nM for contracting chick ileum, which express EP3 receptors. | [Uses]
19(R)-hydroxy PGE1 is the major prostaglandin found in the semen of primates, including man. It is an agonist for the EP1 and EP3 receptor subtypes, and exhibits contractile activity on smooth muscle preparations. It has an EC50 of 320 nM for contracting guinea pig ileum, which express EP1 receptors, and an EC50 of 80 nM for contracting chick ileum, which express EP3 receptors. | [Definition]
ChEBI: 19R-Hydroxy-PGE1 is a prostanoid. | [storage]
Store at -20°C |
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