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ChemicalBook--->CAS DataBase List--->636-88-4

636-88-4

636-88-4 Structure

636-88-4 Structure
IdentificationBack Directory
[Name]

(S)-(+)-NOREPINEPHRINE L-BITARTRATE
[CAS]

636-88-4
[Synonyms]

(+)-Noradrenaline Bitartrate
(S)-(+)-NOREPINEPHRINE L-BITARTRATE
D-Norepinephrine hydrogen tartrate salt
D-Noradrenaline (Norepinephrine) Bitartrate
4-[(1S)-2-amino-1-hydroxy-ethyl]pyrocatechol
4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol
4-[(1S)-2-azanyl-1-hydroxy-ethyl]benzene-1,2-diol
ALPHA-(AMINOMETHYL)-3,4-DIHYDROXYBENZYL ALCOHOL L-BITARTRATE
(S)-beta,3,4-trihydroxyphenethylammonium [R-(R*,R*)]-hydrogen tartrate
(S)-4-(2-amino-1-hydroxyethyl)benzene-1,2-diol(2R,3R)-2,3-dihydroxysuccinate
D-Arterenol hydrogen tartrate salt, D-Noradrenaline hydrogen tartrate salt, D-Norepinephrine bitartrate
D-Noradrenaline L-bitartrate, D-Noradrenaline hydrogen L-tartrate, D-Norepinephrine D-bitartrate, (+)-α-(Aminomethyl)-3,4-dihydroxybenzyl alcohol (+)-tartrate (1:1)
[EINECS(EC#)]

211-268-5
[Molecular Formula]

C16H23NO15
[MDL Number]

MFCD00799001
[MOL File]

636-88-4.mol
[Molecular Weight]

469.35
Chemical PropertiesBack Directory
[Melting point ]

166 °C (dec.)(lit.)
[storage temp. ]

2-8°C
[solubility ]

DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly, Sonicated)
[form ]

Solid
[color ]

White to Off-White
[Optical Rotation]

[α]20/D +38°, c = 1 in H2O
[Stability:]

Hygroscopic
[InChI]

InChI=1/C8H11NO3.C4H6O6/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10)/t8-;1-,2-/s3
[InChIKey]

WNPNNLQNNJQYFA-KBOIKTAVNA-N
[SMILES]

[C@H](O)(C(=O)O)[C@@H](O)C(=O)O.[C@@H](C1C=CC(O)=C(O)C=1)(O)CN |&1:0,5,10,r|
Safety DataBack Directory
[Hazard Codes ]

T,Xn
[Risk Statements ]

25-36/37/38-20/21/22
[Safety Statements ]

36/37-45-37/39-26
[RIDADR ]

UN 2811 6.1/PG 3
[WGK Germany ]

3
[F ]

8-10-23
Hazard InformationBack Directory
[Uses]

(+)-Noradrenaline Bitartrate is an agonist at a1- and a2-adrenoreceptors.
[Purification Methods]

Recrystallise adrenor from EtOH and store it in the dark under N2. [pKa, Lewis Brit J Pharmacol Chemother 9 488 1954, UV: Bergstr.m et al. Acta Physiol Scand 20 101 1950, Fluorescence: Bowman et al. Science NY 122 32 1955, Tullar J Am Chem Soc 70 2067 1948.] The L-tartrate salt monohydrate has m 102-104.5o, [] D -11o (c 1.6, H2O), after recrystallisation from H2O or EtOH. [Beilstein 13 III 2382.]
Spectrum DetailBack Directory
[Spectrum Detail]

(S)-(+)-NOREPINEPHRINE L-BITARTRATE(636-88-4)1HNMR
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