Identification | Back Directory | [Name]
MAGNESIUM DIPROPYLACETATE HYDRATE | [CAS]
62959-43-7 | [Synonyms]
(Mg(II))(Valp)2 Einecs 263-770-9 MAGNESIUM VALPROATE MAGNESIUM DIPROPYLACETATE magnesium 2-propylvalerate MAGNESIUM VALPROATE HYDRATE Valproic acid, magnesium salt MAGNESIUM DIPROPYLACETATE HYDRATE 2-propyl-pentanoicacimagnesiumsalt Pentanoic acid, 2-propyl-, magnesium salt Bis(2-propylpentanoic acid)magnesium salt MAGNESIUM DIPROPYLACETATE HYDRATE USP/EP/BP | [EINECS(EC#)]
263-770-9 | [Molecular Formula]
C16H30MgO4 | [MDL Number]
MFCD06202338 | [MOL File]
62959-43-7.mol | [Molecular Weight]
310.71 |
Chemical Properties | Back Directory | [Melting point ]
>294°C (dec.) | [storage temp. ]
Refrigerator | [solubility ]
Ethyl Acetate (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White | [InChI]
InChI=1S/2C8H16O2.Mg/c2*1-3-5-7(6-4-2)8(9)10;/h2*7H,3-6H2,1-2H3,(H,9,10);/q;;+2/p-2 | [InChIKey]
LKLLHOIUJVEAGU-UHFFFAOYSA-L | [SMILES]
C(CCC)(CCC)C(=O)O[Mg]OC(=O)C(CCC)CCC | [CAS DataBase Reference]
62959-43-7 |
Hazard Information | Back Directory | [Uses]
Antiepileptic | [Uses]
Magnesium Valproate is an anticonvulsant agent and the effects it exerts are the result of valproic acid and magnesium acting in a complementary way. Magnesium valproate is effective as monotherapy in
patients with newly diagnosed or previously treated partial or generalised epilepsy. | [Trade name]
Logical (Armstrong) | [Description]
Valproic acid and its salt Magnesium Valproate is major antiepileptic drugs for the treatment of absence, myoclonic, and generalized tonic – clonic seizures and also may be effective against complex partial seizures. The most cited mechanisms are the increase in GABA function and the blockade of voltage-dependent Na+-channels. The most common side effects are gastrointestinal disturbances and sedation. The most serious adverse effect is liver damage, although this is rare. Teratogenic effects, predominantly spina bifida, are reported frequently. | [Synthesis]
Diethyl malonate is alkylated with 1-bromopropane and then hydrolyzed and decarboxylated to afford Magnesium valproate.
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Company Name: |
Alfa Omega Pharma
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Tel: |
+91-8050045945 +91-9972665399 |
Website: |
www.www.NOWEBSITE |
Company Name: |
Ralington Pharma
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Tel: |
+91-7948911722 +91-9687771722 |
Website: |
www.ralingtonpharma.com |
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