| Identification | Back Directory | [Name]
(4-Chlorophenyl)(3-hydroxyphenyl)methanone | [CAS]
62810-39-3 | [Synonyms]
Pyrotinib Impurity 21
Fenofibrate Impurity 33
-Chloro-3-hydroxy-benzophenone
4’-Chloro-3-hydroxy-benzophenone
(4-Chlorophenyl)(3-hydroxyphenyl)methanone
Methanone, (4-chlorophenyl)(3-hydroxyphenyl)- | [Molecular Formula]
C13H9ClO2 | [MDL Number]
MFCD16316859 | [MOL File]
62810-39-3.mol | [Molecular Weight]
232.66 |
| Hazard Information | Back Directory | [Uses]
4’-Chloro-3-hydroxy-benzophenone is an impurity of Fenofibric acid (F248650), which is an active metabolite of Fenofibrate (F248640). 4’-Chloro-3-hydroxy-benzophenone can also be used to develop treatments for tuberculosis. | [Preparation]
Preparation by diazotization of 3-amino-4?- chlorobenzo-phenone (SM), followed by hydrolysis of the diazonium salt obtained (81%), (84%). SM was obtained by Friedel–Crafts acylation of chlorobenzene with m-nitro-benzoyl chloride, followed by reduction of the resulting 4-chloro- 3?-nitrobenzophenone. |
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