| Identification | Back Directory | [Name]
7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL | [CAS]
6272-55-5 | [Synonyms]
7,8,9,10-tetrahydro-benzo(a)pyren-7-o
Benzo[a]pyren-7-ol, 7,8,9,10-tetrahydro-
7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-7-OL
7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol
7-Hydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene
7,8,9,10-TETRAHYDROBENZO(A)PYREN-7-OL, 9 9% | [Molecular Formula]
C20H16O | [MDL Number]
MFCD00192475 | [MOL File]
6272-55-5.mol | [Molecular Weight]
272.34 |
| Chemical Properties | Back Directory | [Melting point ]
142-144 °C(lit.) | [Boiling point ]
508.5±19.0 °C(Predicted) | [density ]
1.323±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.2 mg/ml | [form ]
A crystalline solid | [pka]
14.36±0.20(Predicted) | [color ]
Light brown to brown |
| Hazard Information | Back Directory | [Description]
7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic sulfuric acid esters, which are capable of forming covalent DNA adducts and inducing mutations. | [Chemical Properties]
Yellow Solid | [Uses]
7,8,9,10-Tetrahydro-benzo[a]pyren-7-ol is a Benzopyrene (B205800) derivative, activated by hepatic cytosol. | [Uses]
7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic sulfuric acid esters, which are capable of forming covalent DNA adducts and inducing mutations.[Cayman Chemical] | [General Description]
7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol (7-hydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene), a polycyclic aromatic hydrocarbon (PAH), is a substituted benzopyrene. Its bromination reaction with N-bromosaccharin (NBSac) has been investigated. The sulfotransferase-assisted activation of 7-hydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene to form electrophilic, mutagenic, or tumorigenic sulfuric acid ester metabolite, which binds covalently to DNA and leads to mutation, has been reported. |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|