| Identification | Back Directory | [Name]
13-Azido-2,5,8,11-tetraoxa-tridecane | [CAS]
606130-90-9 | [Synonyms]
azido-mPEG4
m-PEG4-Azide
MeO-dPEG4)-N3
m-dPEG??-Azide (Azido-m-dPEG??)
13-Azido-2,5,8,11-tetraoxa-tridecane
13-Azido-2,5,8,11-tetraoxatridecane >
O-(2-Azidoethyl)-Oμ-methyl-triethylene glycol
1-azido-2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethane
1-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-2-methoxyethane
m-PEG4-azide (Synonyms: 13-Azido-2,5,8,11-tetraoxatridecane) | [Molecular Formula]
C9H19N3O4 | [MDL Number]
MFCD13184960 | [MOL File]
606130-90-9.mol | [Molecular Weight]
233.265 |
| Hazard Information | Back Directory | [Description]
m-PEG4-azide is a PEG reagent with an azide group. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry. | [Uses]
m-PEG4-azide (13-Azido-2,5,8,11-tetraoxatridecane) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. m-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [reaction suitability]
reaction type: click chemistry
reagent type: cross-linking reagent | [IC 50]
PEGs | [References]
[1] Belen Begines, et al. Synthesis of Reduction Sensitive Comb-Like Polyurethanes Using Click Chemistry. Journal of Polymer Science Part A: Polymer Chemistry, 2016, 54(24), 3888-3900. |
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