| Identification | Back Directory | [Name]
3-HYDROXY-3-METHYL-D3-PENTANEDIOIC ACID | [CAS]
59060-36-5 | [Synonyms]
3-HYDROXY-3-METHYL (D3)GLUTARIC ACID
3-HYDROXY-3-METHYL-D3-PENTANEDIOIC ACID | [Molecular Formula]
C6H7D3O5 | [MDL Number]
MFCD01074174 | [MOL File]
59060-36-5.mol | [Molecular Weight]
165.16 |
| Chemical Properties | Back Directory | [Melting point ]
104-108°C | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Methanol (Slightly), Water (Slightly) | [form ]
solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
Meglutol-d3 is the deuterium labeled Meglutol[1]. Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110 |
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