Hazard Information | Back Directory | [Description]
A 69024 is a highly selective dopamine D-1 receptor antagonist. It is a radioligand that may antagonize self-mutilatory behavior. | [Uses]
A-69024 is a selectivity dopamine D-1 receptor antagonist with the Ki values of 12.6 nM and 1290 nM for dopamine D-1 receptor and dopamine D-2 receptor, respectively[1]. | [IC 50]
D1 Receptor: 12.6 nM (Ki); D2 Receptor: 1290 nM (Ki) | [References]
[1] Kerkman DJ, et al. A-69024: a non-benzazepine antagonist with selectivity for the dopamine D-1 receptor. Eur J Pharmacol. 1989;166(3):481-491. DOI:10.1016/0014-2999(89)90362-2 |
|
|