Identification | Back Directory | [Name]
TA-03 | [CAS]
5778-80-3 | [Synonyms]
TA-03 7-Meota TA 03,TA03 7-Methoxytacrine 7-methoxy-1,2,3,4-tetrahydroacridin-9-amine 9-Acridinamine, 1,2,3,4-tetrahydro-7-methoxy- | [Molecular Formula]
C14H16N2O | [MDL Number]
MFCD01237613 | [MOL File]
5778-80-3.mol | [Molecular Weight]
228.29 |
Hazard Information | Back Directory | [Uses]
7-Methoxytacrine (7-MEOTA) is an inhibitor of human acetylcholinesterase (hAChE) with an IC50 value of 10 μM, and can be used for the research of Alzheimer's disease (AD)[1]. | [IC 50]
hAChE: 10.5 μM (IC50); hBCHE: 21 μM (IC50) | [References]
[1] Spilovska K, et al. 7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer's disease treatment--synthesis, biological evaluation and molecular modeling studies. Molecules. 2013;18(2):2397-2418. Published 2013 Feb 20. DOI:10.3390/molecules18022397 |
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Company Name: |
cjbscvictory
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Tel: |
13348960310 |
Website: |
https://www.weikeqi-biotech.com/ |
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